Sagittal alignment changes and postoperative complications following surgery for adult spinal deformity in patients with Parkinson’s disease: a multi-institutional retrospective cohort study

Abstract Background Parkinson’s disease (PD) has been found to increase the risk of postoperative complications in patients with adult spinal deformity (ASD). However, few studies have investigated this by directly comparing PD and those without PD. Methods In multicenter retrospective cohort study, we reviewed all surgically treated ASD at least 2 years follow-up. Among them, 27 had (PD+ group). Clinical data were collected on early late as well any revision surgery. Radiographic parameters evaluated before immediately after surgery final follow-up, including sagittal vertical axis (SVA), thoracic kyphosis, lumbar lordosis, sacral slope, pelvic tilt. We compared surgical outcomes radiographic non-PD patients. Results For complications, PD+ group demonstrated a higher rate delirium than PD− group. terms non-union was significantly Rates rod failure due mechanical also tended be higher, but not significantly, ( p = 0.17, 0.13, respectively). SVA follow-up loss correction Conclusion Extra attention should paid perioperative especially delirium, undergoing for ASD. Furthermore, greater these